Gloria Arriagada CV

Gloria Arriagada CV

 

Education

 

2001 Licenciado en Bioquimica, Universidad de Concepción

2004 Bioquimico, Universidad de Concepcion

2007 Doctor en Ciencias Biologicas, Universidad de Concepcion

 

Positions

 

2007-June 2012          Postdoctoral Research Scientist, Columbia University

July 2012-present       Instructor, Universidad Andres Bello

 

Honors

 

2001                Premio Universidad de Concepcion

2003                CONICYT fellowship for doctoral studies

2005                CONICYT fellowship for doctoral thesis support

2007                CONICYT fellowship for finalization of doctoral studies

2007-2009      Pew Latin American fellow in the Biomedical Sciences

 

Grants

 

2013    Fondecyt 1130852 “Role of the microtubule motor complex dynein in the infection of the

retroviruses Murine Leukemia Virus”

 

2013   DI-262-13/R “Role of the microtubule motor dynein in HIV-1 infection”

 

Publications

 

Lukic Z, Goff SP, Campbell EM, Arriagada G. Role of SUMO-1 and SUMO interacting motifs in rhesus TRIM5alpha-mediated restriction. Retrovirology 2013 Feb 1;10(1):10

Arriagada G*, Muntean LN*, Goff SP. SUMO-interacting Motifs of Human TRIM5α are Important for Antiviral Activity. PLoS Pathog 7(4): e1002019

Arriagada G, Henriquez B, Moena D, Merino P, Ruiz-Tagle C, Lian JB, Stein GS,  Stein JL, Montecino M. Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D(3)-mediated transcriptional upregulation in osteoblasts. J Steroid Biochem Mol Biol. 2010 Feb23:121(1-2):156-8

Arriagada G, Paredes R, van Wijnen AJ, Lian JB, van Zundert B, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA. J Cell Physiol. 2009 Nov 2;222(2):336-346.

Valente ST, Gilmartin GM, Venkatarama K, Arriagada G, Goff SP. HIV-1 mRNA 3′ end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8. Mol Cell. 2009 Oct 23;36(2):279-89.

Montecino M, Stein GS, Stein JL, Lian JB, van Wijnen AJ, Carvallo L,Marcellini S, Cruzat F, Arriagada G. Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery. Crit Rev Eukaryot Gene Expr. 2008;18(2):163-72.

Arriagada G, Paredes R, Olate J, van Wijnen A, Lian JB, Stein GS, Stein JL, Onate S, Montecino M. Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators.  J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):425-9

Montecino M, Stein GS, Cruzat F, Marcellini S, Stein JL, Lian JB, van WijnenAJ, Arriagada G. An architectural perspective of vitamin D responsiveness. Arch Biochem Biophys. 2007 Apr 15;460(2):293-9

Bruna C, Arriagada G, Lian JB, Stein GS, Bunster M, Martinez-Oyanedel J, Montecino M. Crystallization and preliminary X-ray analysis of a domain in the Runx2 transcription factor that interacts with the 1alpha,25 dihydroxy vitamin D3 receptor. J Cell Biochem. 2007 Jun 1;101(3):785-9.

Paredes R*, Arriagada G*, Cruzat F, Villagra A, Olate J, Zaidi K, van Wijnen A, Lian JB, Stein GS, Stein JL, Montecino M. Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells. Mol Cell Biol. 2004 Oct;24(20):8847-61.

Paredes R, Arriagada G, Cruzat F, Olate J, Van Wijnen A, Lian J, Stein G, Stein J, Montecino M. The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):269-71.

Sierra J, Villagra A, Paredes R, Cruzat F, Gutierrez S, Javed A, Arriagada G, Olate J, Imschenetzky M, Van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Mol Cell Biol. 2003 May;23(9):3339-51